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Dengue Diagnostics The Right Test at the Right Time for the Right Group 1st Edition by Shamala Devi Sekaran ISBN 9781032669564 9814968978

Name: Dengue Diagnostics The Right Test at the Right Time for the Right Group 1st Edition by Shamala Devi Sekaran ISBN 9781032669564 9814968978
SKU: EB-54227598
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Dengue Diagnostics The Right Test at the Right Time for the Right Group 1st Edition Shamala Devi Sekaran Digital Instant Download

Author(s): Shamala Devi Sekaran

ISBN(s): 9789814968973, 9781032669564, 9814968978, 103266956X

Edition: 1

File Details: PDF, 23.98 MB

Year: 2023

Language: English

SKU: EB-54227598 Category: Medicine - Infectious diseases Tag: Shamala Devi Sekaran

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Dengue Diagnostics The Right Test at the Right Time for the Right Group 1st Edition by Shamala Devi Sekaran – Ebook PDF Instant Download/Delivery: 9781032669564 ,9814968978
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ISBN 10: 9814968978
ISBN 13: 9781032669564
Author: Shamala Devi Sekaran

Diagnostics plays a vital role in identifying infectious diseases that have the potential to become an epidemic, such as dengue. Good diagnostics enables identifying the cause of an outbreak and assessing interventions for a better impact. The dengue virus is a member of the family of flaviviruses that cross-reacts serologically with all members of its family. The presenting symptoms do not allow definitive diagnosis because they can be of malaria, dengue, Zika, chikungunya, or one of a host of other possibilities. In children, efficient and accurate dengue diagnostics is very important for the early confirmation of dengue because of its quick progress to severe dengue. Dengue diagnostic assays are wide-ranging―from being a reliable one that is time-consuming and expensive to rapid test kits that substantially vary in their accuracy. Therefore, it is important to know which test is to be used at what time, considering whether the population is in an endemic area, as well as how and when to use these tests, be it for the virus or for its genome, antigens, or antibodies. An ideal diagnostic test is one that can pick the virus early enough, is rapid and easy to perform, and affordable by all communities but such a test is yet not available. This book deals with most of the methods that have been used or developed for diagnosing dengue. It addresses the timeline for the evolution of the virus in the body, the body’s response from the onset of fever, and the role of diagnostics as time progresses. It covers most methods, detailing selected protocols, as well as compares them and assesses the time point at which they are useful. The book will be helpful in determining the right test, at the right time, for the right population.

Dengue Diagnostics The Right Test at the Right Time for the Right Group 1st Edition Table of contents:

Chapter 1: Introduction to Dengue Fever
1.1 Understanding Dengue: Causes and Transmission
1.2 Clinical Manifestations of Dengue Fever
1.3 The Global Impact of Dengue: Epidemiology and Statistics
1.4 The Importance of Timely Diagnosis in Disease Management

Chapter 2: Overview of Dengue Diagnostics
2.1 The Need for Accurate and Timely Diagnostic Tools
2.2 Types of Diagnostic Methods for Dengue
2.3 Challenges in Dengue Diagnosis: Sensitivity, Specificity, and Timing
2.4 A Brief History of Dengue Diagnostic Technologies

Chapter 3: Laboratory Techniques for Dengue Diagnosis
3.1 Serological Methods: Enzyme-Linked Immunosorbent Assay (ELISA)
3.2 Molecular Techniques: Polymerase Chain Reaction (PCR)
3.3 Virus Isolation and Antigen Detection
3.4 Immunohistochemistry and Microscopic Methods
3.5 Advances in Next-Generation Sequencing for Dengue

Chapter 4: Serological Tests for Dengue Diagnosis
4.1 Dengue IgM and IgG Antibodies: What They Indicate
4.2 The Timing of IgM and IgG Tests in Diagnosis
4.3 Limitations of Serological Testing and Cross-Reactivity
4.4 Interpreting Serological Results in Different Stages of Disease
4.5 Novel Approaches to Improve Serological Testing Accuracy

Chapter 5: Molecular Diagnostics: PCR and Beyond
5.1 Polymerase Chain Reaction (PCR) in Dengue Diagnosis
5.2 Reverse Transcription PCR (RT-PCR) for Detecting Viral RNA
5.3 Quantitative PCR and Viral Load Measurement
5.4 Point-of-Care Molecular Diagnostics: Field Use Considerations
5.5 Pros and Cons of PCR-Based Diagnostic Methods

Chapter 6: Antigen Detection and Rapid Diagnostic Tests
6.1 Antigen Detection Methods for Early Diagnosis
6.2 Lateral Flow Immunoassays: A Popular Diagnostic Tool
6.3 Rapid Diagnostic Kits (RDTs): Practical Application in Resource-Limited Settings
6.4 Sensitivity, Specificity, and Validation of Rapid Tests
6.5 Evaluating the Effectiveness of Antigen Tests in Field Situations

Chapter 7: The Right Diagnostic Test at the Right Time
7.1 Determining the Appropriate Test Based on Symptom Onset
7.2 Early vs. Late Stage Diagnosis: Testing Protocols
7.3 Test Selection for Different Population Groups: Adults, Children, Pregnant Women
7.4 Case Studies: Real-Life Applications of Timely Diagnostic Testing
7.5 Optimizing Diagnosis for Effective Disease Management

Chapter 8: Diagnostic Tools for Special Populations
8.1 Diagnosing Dengue in Children and Neonates
8.2 Pregnancy and Dengue: Special Considerations in Diagnostics
8.3 Elderly Patients: Diagnostic Challenges and Considerations
8.4 Diagnosing Co-Infections with Dengue: Malaria, Zika, and Chikungunya
8.5 Testing in Resource-Limited Settings: Strategies and Innovations

Chapter 9: Emerging Trends and Future Directions in Dengue Diagnostics
9.1 Innovative Diagnostic Technologies on the Horizon
9.2 Point-of-Care and Field Diagnostics: Moving Towards Accessibility
9.3 Integration of Diagnostic Tools with Surveillance Systems
9.4 The Role of Artificial Intelligence and Machine Learning in Dengue Diagnosis
9.5 Global Efforts to Improve Dengue Diagnostic Capabilities

Chapter 10: Implementing Dengue Diagnostic Strategies in Public Health
10.1 The Role of Diagnostic Strategies in Dengue Control Programs
10.2 Surveillance and Monitoring: Using Diagnostics for Effective Tracking
10.3 Cost-Effective Diagnostics in Endemic Regions
10.4 Training and Capacity Building for Health Care Providers
10.5 Collaborations Between Governments, NGOs, and Researchers

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