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Fast Facts Bladder Cancer Third Edition Seth P Lerner

Name: Fast Facts Bladder Cancer Third Edition Seth P Lerner
SKU: EB-36422138
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Fast Facts Bladder Cancer Third Edition Seth P Lerner Digital Instant Download

Author(s): Seth P Lerner; Ian D Davis

ISBN(s): 9781910797648, 1910797642

Edition: 3

File Details: PDF, 2.95 MB

Year: 2021

Language: English

SKU: EB-36422138 Category: Medicine - Clinical Medicine Tags: 1910797642, 9781910797648, Bladder Cancer, Fast Facts, Ian D Davis, Seth P Lerner

Description

Fast Facts Bladder Cancer Third Edition Seth P Lerner – Ebook Instant Download/Delivery ISBN(s): 9781910797648,1910797642

Product details:

• ISBN 10:1910797642
• ISBN 13:9781910797648
• Author(s): Seth P Lerner; Ian D Davis

Our understanding of the biology of bladder cancer has advanced remarkably since the second edition of Fast Facts: Bladder Cancer was published in 2006. Five new immunotherapies targeting the PD-1 axis were approved in 2016 and 2017 for the treatment of advanced bladder cancer, reflecting this transformative explosion in knowledge about the biology of the disease. This new era of targeted treatment offers hope to patients, particularly those with advanced disease. However, for clinicians it means a lot to understand in terms of how these immunotherapies are integrated into the treatment paradigm. Who they are suitable for? When are they best used? What is the optimal sequence of treatments for individual patients? This third edition of Fast Facts: Bladder Cancer has been updated extensively throughout by two new authors, bringing a fresh perspective. Key updates include: • the latest understanding of pathology and biology • current standards for investigation, imaging and diagnosis • the critical role that awareness of the significance of hematuria among patients and primary care health professionals can make to earlier detection at curable stages of the disease • the roles of drugs, surgery and radiation therapy in treatment at different stages of bladder cancer, and when and how best to intervene, aided by understanding of the risk factors for disease relapse and progression • a new chapter about immunotherapy for bladder cancer • future trends in a rapidly evolving field. Fast Facts: Bladder Cancer is a concise guide that will be of value to clinicians and health professionals involved in the detection and treatment of bladder cancer. This highly readable resource provides a comprehensive and current view of this complex disease, enabling informed discussions with patients.

Table contents:

Glossary
Introduction
Epidemiology and etiology
Epidemiology
Etiology
Pathology and biology
Histology
Staging and grading
Molecular phenotype
Patterns of recurrence and spread
Mortality
Clinical presentation
Painless hematuria
Asymptomatic microscopic hematuria
Irritative symptoms
Recurrent urinary tract infections
Symptoms of local or distant spread
Delay in diagnosis
Investigations
History
Examination
Detailed investigation
Management of non-muscle-invasive disease
Basic principles
Initial surgical management
Prognostic factors
Prognostic groups
Intravesical therapy
Surveillance following initial diagnosis and treatment
Management of muscle-invasive disease
Radical cystectomy and pelvic lymphadenectomy
Peri-operative treatment for intermediate- or high-risk bladder cancer
Multimodality and bladder-preserving therapy
Management of advanced and metastatic disease
Systemic therapy for metastatic bladder cancer
Second and subsequent lines of chemotherapy
General principles of treatment
Palliation and best supportive care
Immunotherapy
Principles of immunotherapy
PD-1 axis
PD-1-targeted immunotherapies
Prediction of response
First-line studies
Adverse effects of immunotherapy
Future trends
Improving prevention
Earlier diagnosis
Better treatment of high-risk non-muscle-invasive disease
Improved use of existing therapies
Identification of biomarkers that allow better risk stratification and treatment selection
Development of new therapies and rational combinations
Better involvement of palliative and supportive care
Useful resources
Index