Genes A Very Short Introduction 2nd Edition by Jonathan Slack 0192856707 9780192856708

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ISBN 10: 0192856707

ISBN 13: 9780192856708

Author: Jonathan Slack

Very Short Introductions: Brilliant, Sharp, Inspiring In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development. By explaining the nature of genetic variation in the human population, how hereditary factors were identified as molecules of DNA, and how certain specific mutations can lead to disease, Slack highlights how DNA variants are used to trace human ancestry and migration, and can also be used by forensic scientists to identify individuals in crime. He also explores issues such as the role of genetic heritability and IQ as well as the changes that occur in the genes of populations during evolution. An ideal guide for anyone curious about what genes are and how genetics can be put to use, this Very Short Introduction demonstrates the ways in which the gene concept has been understood and used by molecular biologists, population biologists, and social scientists around the world. This second edition has been fully updated and contains new sections on the CRISPR method for targeted genetic modification, on DNA profiling, and developments in our understanding of human ancestry using ancient DNA. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Genes A Very Short Introduction 2nd Table of contents:

Chapter 1. Genes before 1944

Biology of heredity

The 20th century

DNA

The chemical nature of the gene

Chapter 2. Genes as DNA

The double helix

What is a gene?

DNA during cell division

Genomics

How genes make animals

DNA methylation

Implications of understanding development

The human genome

Genetic modification

Chapter 3. Mutations and gene variants

Mutations

Gene variants in populations

Cystic fibrosis

Haemophilia

Achondroplasia

Features of genetic disease

Genetic predisposition and cancer

More complex genetic variation

Chapter 4. Genes as markers

Forensic identification

Forensic phenotyping

Ancestry and migration

Mitochondrial DNA

Y chromosome

Geographical history of humanity

Race

Genetic ancestry testing

Ancient DNA

Meet the Denisovans

Chapter 5. Genes of small effect

Heritability

Genome-wide association studies (GWAS)

Human height

Mental illness

The ‘gay gene’

IQ

Group differences in IQ

Prediction of risks or qualities from DNA

Chapter 6. Genes in evolution

Neutral evolution

Classification of organisms

Implications of natural selection

Problematic types of selection

Sex

Altruism

Universal characters ascribed to ‘genes’

Conclusion: the varied concepts of the gene

Glossary

Further reading

Index

Forensic Science

Autism

Cancer

The History of Medicine

Science and Religion

Scientific Revolution

Epidemiology

Relativity

The Laws of Thermodynamics

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