Inflammation and Natural Products 1st Edition by Sreeraj Gopi, Augustine Amalraj, Ajaikumar B Kunnumakkara, Sabu Thomas ISBN 9780128192184 0128192186

Inflammation and Natural Products 1st Edition by Sreeraj Gopi, Augustine Amalraj, Ajaikumar B Kunnumakkara, Sabu Thomas – Ebook PDF Instant Download/Delivery: 9780128192184 ,0128192186
Full download Inflammation and Natural Products 1st Edition after payment

Product details:
ISBN 10: 0128192186
ISBN 13: 9780128192184
Author: Sreeraj Gopi, Augustine Amalraj, Ajaikumar B Kunnumakkara, Sabu Thomas

Inflammation and Natural Products 1st Edition Table of contents:

Inflammation, symptoms, benefits, reaction, and biochemistry
Introduction
Causes and symptoms of inflammation
Types of inflammation
Acute inflammation
Chronic inflammation
Primary chronic inflammation
Secondary chronic inflammation
Benefits of inflammation
Inflammation as a necessary evil
Indicative of chronic diseases
Cancer
Cardiovascular diseases
Neurodegenerative and Alzheimer’s diseases
Autoimmune diseases
Inflammatory bowel diseases (IBD)
Reactions and biochemistry
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF- κ B)
Cytokines
Tumor necrosis factor alpha (TNF- α)
Protein kinase
P38 mitogen-activated protein kinase (MAPK)
CD8 + T cells
Regulatory T cells (Treg cells)
Toll-like receptor ligand (TLR)
G protein-coupled receptors (GPCRs)
Conclusion
References
Molecular pharmacology of inflammation: Medicinal plants as antiinflammatory agents
Introduction
Antiinflammatory agent molecular targets
Inflammatory mediators, receptors, and major signaling pathways
Cytokines
TNF α
Interleukins
Chemokines
TGF β
Transcription factors
NF- κ B
STATs
Hypoxia-inducible factor HIF
Complement activation pathways
Eicosanoids
Reactive oxygen species (ROS) and reactive nitrogen species (RNS)
Toll-like receptors
Cell signaling pathways involved in inflammation
The NF- κ B pathway
Mitogen-activated protein kinase (MAPK) pathway
The JAK-STAT pathway
The Phosphatidylinositol-3-kinase (PI3K)/Akt pathway
The arachidonic acid pathway
Other pathways associated with inflammation
Antiinflammatory potential of medicinal plants and their active constituents
Inflammatory pathways as potential targets for natural bioactive compounds
Antiinflammatory activity of natural bioactive compounds
Conclusion
Acknowledgments
Conflict of interest
References
Natural products with antiinflammatory activities against autoimmune myocarditis
Introduction
Myocarditis
Etiology and pathogenesis of autoimmune myocarditis
Antiinflammatory mechanism for autoimmune myocarditis
Inhibition of regulatory T helper cells
Inhibition of cytokines and macrophage infiltration
Natural products renowned for antiinflammatory activity
Curcuma longa L. (curcumin)
Cannabis sativa /marijuana (cannabidiol)
Berberine
Resveratrol
Emodin
Radix Astragali
Catechins
Mulberry leaf
Oleanolic acid
Conclusion
References
Multitarget approach for natural products in inflammation
Introduction
Mechanisms: Mediators and pathways behind inflammation
Activation of pattern recognition receptors (PRRs) on cells
NF- κ B pathway
MAPK (ERK) pathway
JAK-STAT pathway
Nitric oxide (NO)
Eicosanoids and arachidonic acid (AA) pathway
Other inflammatory markers
Cyclooxygenase-2 (COX-2)
Cytokines
Other inflammatory proteins and enzymes
Antiinflammatory Kelch-like ECH-associated protein 1 (Keap1)-nuclear factor erythoid-2-related factor 2 (Nrf2)-a …
Distinct pathways behind neuroinflammation; Alzheimer’s disease as a case
Multitarget approach for antiinflammatory action
Natural compounds with multitarget in antiinflammation
Curcuminoids
Fucoxanthin
Quercetin
Resveratrol
Ginsenosides
Phlorotannins
Catechin and derivatives
Withaferin A
Combination of phytochemicals
Conclusion
References
Antiinflammatory activity of natural dietary flavonoids
Introduction
Flavonoids and cardiovascular diseases
Flavonoids and diabetes mellitus
Flavonoids and gastrointestinal diseases
Conclusion and perspectives
References
Antiinflammatory effects of turmeric ( Curcuma longa) and ginger ( Zingiber officinale)
Introduction
Turmeric
Morphology and taxonomy of genus Curcuma
Composition of turmeric
Mechanisms of action
Molecular mechanism and biochemical changes
Safety of curcumin
Ginger ( Zingiber officinale)
Morphology
Taxonomic position
Cultivation
Stability
Nutrient profile and active components
Chemical composition
Dosage
Mechanism of action of ginger and its constituents
Antiinflammatory effect of ginger
Conclusion
References
Antiinflammatory activity of Boswellia
Introduction
Taxonomy and phytochemistry
Pharmacological activities of Boswellia
Molecular targets of boswellic acids and mechanism of action of boswellic acids
Bioavailability
Preclinical studies
Clinical studies of the antiinflammatory action
Toxicity and side effects in clinical evaluations
Conclusion
References
Antiinflammatory activity of galangal
Introduction
Phytochemistry
Mechanism of antiinflammatory pathway
Pharmacological activities
Preclinical studies
Clinical studies
Usage in traditional systems
Toxicity studies
Conclusion
References
Antiinflammatory natural products from marine algae
Introduction
Inflammation
Antiinflammatory agents
Algal natural products with antiinflammatory activity
Polysaccharides
Fatty acids and lipid derivatives
Proteins and peptides
Phenolic compounds
Terpenoids, sterols, and carotenoids
Alkaloids
Other secondary metabolites possessing antiinflammatory activity
Conclusions
Conflict of interest
References
Medicinal plants and their potential use in the treatment of rheumatic diseases
Introduction
Herbal products currently used in antiarthritic therapy
Boswellia serrata Roxb.
Curcuma longa Linn.
Cinnamomum zeylanicum Blume
Echinodorus grandiflorus (Cham. & Schltdl.) Micheli.
Colchicum luteum Baker
Tripterygium wilfordii Hook F.
Andrographis paniculata (Burm. fil.) Nees
Nigella sativa L.
Conclusion and perspectives
References
Natural product–derived drugs for the treatment of inflammatory bowel diseases (IBD)
Introduction
Epidemiology
Pathogenesis
Crohn’s disease
Ulcerative colitis
The role of natural products on IBD
Natural products for ulcerative colitis and Crohn’s disease
Aloe vera
Artemisia absinthium (Compositae)
Boswellia spp.
Butyrate
Licorice
Slippery elm ( Ulmus fulva)
Tormentil extracts
Triticum aestivum (wheatgrass)
Cannabis sativa (Cannabaceae)
Curcuma longa (Zingiberaceae)
Germinated barley foodstuff
Bromelain
Psyllium
Withania somnifera
Plant tannins
Guggulsterone
Agaricus subrufescens ( Agaricus blazei)
Fufangkushen colon-coated capsule
Andrographis paniculata (Acanthaceae)
Jian Pi Ling
Xilei-san
Anthocyanin-rich bilberry preparation
Plantago ovata (Plantaginaceae)
Oenothera biennis
Bunium persicum
Cassia fistula
Cydonia oblonga
Solanum nigrum
Juglans regia
Althaea spp.
Conclusion remarks and future perspective
References
Smart drug delivery systems of natural products for inflammation: From fundamentals to the clinic
Introduction
Stimuli-responsive drug delivery system
Internally responsive drug delivery system
Redox-responsive drug delivery system
Enzyme-responsive drug delivery system
pH-responsive drug delivery system
Thermo-responsive drug delivery system
Light-responsive drug delivery system
Externally responsive drug delivery system
Ultrasonic-responsive drug delivery system
Magnetically responsive drug delivery system
Conclusion
References
Systems pharmacology and molecular docking strategies prioritize natural molecules as antiinflammatory agents
Introduction
Systems pharmacology and antiinflammatory agents
Computational methodologies and molecular docking studies with natural compounds
Inflammatory pathway network and key node targets of antiinflammatory agents
Cyclooxygenase-2 (COX-2)
Phospholipase A2 (PLA2)
NF- κ B-inducing kinase (NIK)
Interleukin-1 receptor-associated kinase-4 (IRAK-4)
Dihydrofolate reductase (DHFR)
5-Lipooxygenase (5-LOX)
Prioritization strategy and systems pharmacology approach for screening of potential therapeutic agents
Target prediction and pathway enrichment analysis
Systems biology approach for target prioritization and molecular docking
Database-mediated compound target/activity prioritization
Natural compounds and their interactions in the inflammatory pathway network and prioritization as antiinflammato …
Turmeric bioactives targeting the inflammatory pathway network
Ginger bioactives targeting the inflammatory pathway network
Boswellia bioactives targeting the inflammatory pathway network
Galangal bioactives targeting the inflammatory pathway network
Rosemary bioactives targeting the inflammatory pathway network
Conclusion
References
Bioavailability, pharmacokinetic, pharmacodynamic, and clinical studies of natural products on their antiinflammatory activ …
Introduction
Antiinflammatory activities of natural products
Angelica sinensis (Oliv.) Diels (Angelica root)
Pharmacokinetics and bioavailability
Pharmacodynamics
Astragalus membranaceus (Astragalus)
Pharmacokinetics and bioavailability
Pharmacodynamics
Curcuma longa L. (Curcumin)
Pharmacokinetics and bioavailability
Pharmacodynamics
Salvia miltiorrhiza (Danshen)
Pharmacokinetics and bioavailability
Pharmacodynamics
Echinacea purpurea (Echinacea)
Pharmacokinetics and bioavailability
Pharmacodynamics
Allium sativum L. (garlic)
Pharmacokinetics and bioavailability
Pharmacodynamics
Zingiber officinale roscoe (ginger)
Pharmacokinetics and bioavailability
Pharmacodynamics
Ginkgo biloba L. (Ginkgo biloba)
Pharmacokinetics and bioavailability
Pharmacodynamics
Panax ginseng Meyer (ginseng)
Pharmacokinetics and bioavailability
Pharmacodynamics
Silybum marianum (L.) Gaertn. (Milk thistle)
Pharmacokinetics and bioavailability
Pharmacodynamics
Conclusion
References
Supplements and diets for antiinflammation
Introduction
Types of inflammatory
Acute inflammation
Chronic inflammation
Antiinflammatory supplements
Omega-3 fatty acid
Turmeric
Ginger
Probiotic
White willow bark
Green tea
Capsaicin
Seaweeds
Brahmi
Ocimum sanctum L.
Role of diet in body inflammation
Nutrient effects on chronic inflammation
Conclusion
References
Values of natural products to future antiinflammatory pharmaceutical discovery
Introduction
Inflammatory mediators
Antiinflammatory therapy and response
Nonsteroidal antiinflammatory drugs vs inflammation
Biodiversity of plant natural products
Medicinal plants as gift of nature
Herbal remedies in traditional medication for inflammation
Ayurvedic formulation for inflammation
Natural products—A promising antiinflammatory pharmaceutical drug discovery
Turmeric—Curcuminoids
Boswellia serrata
Kaempferia galanga
Pepper
Ginger
Rosemary
Major challenges in upgrading natural products
Future prospective and conclusions
References
Identification of toxicology biomarker and evaluation of toxicity of natural products by metabolomic applications
Background
Metabolomic technology
Sample preparation
Data analysis
Metabolomics in toxicity evaluation and biomarker identification of natural products
Metabolomics in nephrotoxicity evaluation of natural products
Metabolomics in hepatotoxicity evaluation of natural products
Metabolomics in cardiotoxicity evaluation of natural products
Metabolomics in other toxicity evaluation of natural products
Concluding remarks and perspectives
References
Index

People also search for Inflammation and Natural Products 1st Edition:

natural inflammatory
    
natural inflammation pills
    
a natural anti-inflammatory supplement
    
quercetin and inflammation
    
quell inflammation

Tags: Sreeraj Gopi, Augustine Amalraj, Ajaikumar B Kunnumakkara, Sabu Thomas, Natural Products