Laboratory Medicine in Psychiatry and Behavioral Science 2nd Edition by Sandra A Jacobson ISBN 9781615374519 1615374515
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ISBN 10: 1615374515
ISBN 13: 9781615374519
Author: Sandra A Jacobson
The past decade has seen a proliferation of research and publication related to laboratory science and psychiatry. Those advances are now captured in this revised second edition of Laboratory Medicine in Psychiatry and Behavioral Science.
Backed by years of clinical practice and research in neuropsychiatry and informed by literature from the National Library of Medicine as well as sources such as the American Society of Health-System Pharmacists Drug Information book, online resources from ARUP Laboratories, and the American Association for Clinical Chemistry, this volume is designed to assist psychiatrists and other behavioral health clinicians in the care of adult psychiatric patients across a wide range of settings.
With the same comprehensive approach that was a hallmark of the first edition, this edition features new sections on COVID-19, 22q11.2 deletion syndrome, and DRESS syndrome, as well as updated descriptions of
• Laboratory tests, from CT angiography and blood alcohol level to electrocardiograms and a renal function panel• Diseases and conditions, including Alzheimer’s disease, autism spectrum disorder, HIV and AIDS, and schizophrenia• Screening and monitoring of psychotropic medications, including benzodiazepines, fluoxetine, naltrexone, and vardenafil
- Readers can be confident that the provided information is relevant to their daily practice: The included laboratory tests were chosen because they are core for any patient, are novel in medicine, or are particularly pertinent to psychiatry or behavioral health. Similarly, the diseases and conditions described are those for which laboratory tests are important in diagnosis or differential diagnosis; those that are common among psychiatric or geriatric patients; and those that have significant psychiatric, cognitive, or behavioral consequences.
With appendixes that contain algorithms, tables, and figures that will aid in understanding and interpreting various laboratory tests and their underlying biology, this volume sets itself apart from any other reference and is an indispensable resource for anyone in general psychiatric practice, from trainees to physician assistants and advanced practice nurses.
Laboratory Medicine in Psychiatry and Behavioral Science 2nd Edition Table of contents:
Chapter 1. Laboratory Tests
Adrenocorticotropic hormone (ACTH)
Alanine transaminase (ALT)
Albumin
Aldosterone
Alkaline phosphatase (ALP)
Alprazolam level
Ammonia
Amylase
Angiography, computed tomography (cerebrovascular)
Angiography, magnetic resonance (cerebrovascular)
Antidiuretic hormone (ADH)
Antinuclear antibody (ANA) testing
Antiphospholipid (aPL) antibodies
Apolipoprotein E (ApoE) genotyping
Aspartate transaminase (AST)
Basic metabolic panel (BMP)
Bile acids
Bilirubin
Blood alcohol level (BAL)
Blood gases
Blood urea nitrogen (BUN)
Bone mineral density scan
Brain natriuretic peptide (BNP)
Calcium
Carbamazepine level
Carbohydrate-deficient transferrin (CDT)
Carbon dioxide (CO2)
Carotid ultrasound
Cerebrospinal fluid amyloid-β1–42 (CSF Aβ1–42)
Cerebrospinal fluid analysis
Cerebrospinal fluid cell count and differential
Cerebrospinal fluid cytology
Cerebrospinal fluid glucose
Cerebrospinal fluid lactate
Cerebrospinal fluid protein
Cerebrospinal fluid tau protein
Chest X-ray (CXR)
Chlordiazepoxide level
Chloride
Cholinesterase
Clonazepam level
Clozapine level
Complete blood count (CBC)
Comprehensive metabolic panel (CMP)
Computed tomography scan, head
Cortisol
C-reactive protein (CRP)
Creatine kinase (CK)
Creatinine
Cystatin-C
Cytochrome P450 (CYP450) genotyping
Dexamethasone suppression test (DST)
Diazepam level
Echocardiogram
Electrocardiogram
Electroencephalogram (EEG)
Electrolytes panel
Electromyography (EMG) and nerve conduction testing (NCT)
Erythrocyte sedimentation rate (ESR)
Estrogens
Ethylene glycol level
Event-related potential (ERP) testing
Evoked potential (EP) testing
Fecal blood testing
Ferritin
Flurazepam level
Folate level
Follicle-stimulating hormone (FSH)
Fragile X DNA testing
Functional magnetic resonance imaging (fMRI)
Gamma-glutamyltransferase (GGT)
Glucose
Heavy metal screening
Hematocrit
Hemoglobin
Hemoglobin A1C (HbA1C)
Hepatitis panel
High-sensitivity C-reactive protein (hsCRP)
HIV testing
Homocysteine level
Human chorionic gonadotropin (hCG)
Human growth hormone level
Huntingtin gene mutation
Iron level
Lipase
Lipid panel
Lithium level
Liver function tests (LFTs)
Lorazepam level
Lyme antibodies
Magnesium
Magnetic resonance imaging
Magnetic resonance spectroscopy (MRS)
Mammography
Mean corpuscular volume (MCV)
Metanephrines
Methanol level
Methylmalonic acid (MMA) level
Multiple sleep latency test (MSLT) and maintenance of wakefulness test (MWT)
Osmolality
Oxazepam level
Parathyroid hormone (PTH)
Phosphate
Platelet count
Polysomnography
Positron emission tomography, brain
Potassium
Prealbumin
Prolactin
Prostate-specific antigen (PSA)
Protein, serum
Pyridoxine (vitamin B6) level
Quantitative electroencephalogram (qEEG)
Red blood cell (RBC) count
Renal function panel
Reticulocyte count
Serotonin transporter polymorphism
Single-photon emission computed tomography
Sodium
Syphilis testing
Temazepam level
Testosterone level
Thiamine level
Thyroid function testing: free thyroxine
Thyroid function testing: thyroid-stimulating hormone (TSH)
Total iron-binding capacity (TIBC)
Transferrin; transferrin saturation
Triglycerides
Troponins
Tuberculosis (TB) testing
Uric acid
Urinalysis
Urine appearance
Urine bilirubin
Urine blood, hemoglobin, and myoglobin
Urine casts
Urine color
Urine crystals
Urine dipstick testing
Urine drug screen
Urine epithelial cells and epithelial casts
Urine glucose
Urine ketones
Urine leukocyte esterase
Urine microalbumin
Urine nitrite
Urine pH
Urine protein
Urine red blood cells (RBCs) and RBC casts
Urine specific gravity
Urine white blood cells (WBCs) and WBC casts
Urobilinogen
Valproate level
Vitamin B12 level
Vitamin D level
White blood cell (WBC) count
White blood cell (WBC) count differential: basophils
White blood cell (WBC) count differential: eosinophils
White blood cell (WBC) count differential: lymphocytes
White blood cell (WBC) count differential: monocytes
White blood cell (WBC) count differential: neutrophils
Chapter 2. Diseases and Conditions
22q11.2 deletion syndrome
Adrenal insufficiency (AI)
Alcohol use disorder (AUD)
Aluminum toxicity
Alzheimer’s disease (AD)
Anemia
Anorexia nervosa (AN)
Antiphospholipid syndrome (APS)
Anxiety disorder due to another medical condition; substance/medication-induced anxiety disorder
Attention-deficit/hyperactivity disorder in adults
Autism spectrum disorder (ASD)
Bipolar and related disorder due to another medical condition
Brain abscess
Brain tumor
Bulimia nervosa (BN)
Catatonia
Central pontine myelinolysis (CPM)
Chronic fatigue syndrome (CFS)
Chronic traumatic encephalopathy (CTE)
Cirrhosis
COVID-19
Creutzfeldt-Jakob disease (CJD)
Cushing’s syndrome (CS)
Delirium
Dementia
Dementia with Lewy bodies (DLB)
Depressive disorder due to another medical condition
Diabetes insipidus (DI)
Diabetes mellitus (DM)
Down syndrome (DS)
DRESS syndrome
Drug abuse
Drug-induced liver injury (DILI)
Dysphagia
Encephalitis, viral
Ethylene glycol poisoning
Fatty liver disease
Folate deficiency
Fragile X syndrome (FXS)
Frontotemporal dementia (FTD)
Generalized anxiety disorder (GAD)
Hashimoto’s encephalopathy
Headache
Hemochromatosis
Hepatic encephalopathy (HE)
Hepatitis, viral
HIV and AIDS
Huntington’s disease (HD)
Hydrocephalus
Hypercalcemia
Hyperglycemia
Hyperkalemia
Hypermagnesemia
Hypernatremia
Hyperparathyroidism
Hypertensive encephalopathy
Hypocalcemia
Hypoglycemia
Hypogonadism
Hypokalemia
Hypomagnesemia
Hyponatremia
Hypoparathyroidism
Hypothyroidism
Infectious mononucleosis (IM)
Insomnia disorder
Klinefelter’s syndrome
Lead poisoning
Limbic encephalitis (LE)
Lyme disease
Major depressive disorder (MDD)
Manganese poisoning
Manic episode
Marchiafava-Bignami disease (MBD)
Meningitis
Mercury poisoning
Metabolic syndrome
Metachromatic leukodystrophy (MLD)
Methanol poisoning
Mild neurocognitive disorder
Multiple sclerosis (MS)
Myocardial infarction (MI)
Narcolepsy
Neuroleptic malignant syndrome (NMS)
Neuromyelitis optica spectrum disorder (NMOSD)
Obsessive-compulsive disorder
Obstructive sleep apnea (OSA)
Organophosphate poisoning
Osteoporosis
Pancreatitis, acute
Pancreatitis, chronic
Panic attack and panic disorder
Parkinson’s disease (PD)
Pellagra
Peripheral neuropathy
Pheochromocytoma
Pica
Porphyria
Prader-Willi syndrome (PWS)
Progressive multifocal leukoencephalopathy (PML)
Psychogenic polydipsia
Psychotic disorder due to another medical condition
Pyridoxine deficiency
Restless legs syndrome (RLS)
Sarcoidosis
Schizophrenia
Seizures
Stroke
Subdural hematoma (SDH)
Syndrome of inappropriate antidiuresis (SIAD)
Syphilis
Systemic lupus erythematosus (SLE)
Thiamine deficiency
Thrombocytopenia
Thrombocytosis
Thyrotoxicosis
Tuberculosis (TB)
Uremic syndrome
Urinary tract infection (UTI)
Vitamin B12 deficiency
Wernicke’s encephalopathy (WE) and Wernicke-Korsakoff syndrome
Wilson’s disease
Chapter 3. Psychotropic Medications: Laboratory Screening and Monitoring
Acamprosate
Amphetamines
Antipsychotics, first generation
Aripiprazole
Asenapine
Atomoxetine
Benzodiazepines
Bremelanotide
Brexpiprazole
Buprenorphine
Bupropion
Buspirone
Carbamazepine
Cariprazine
Citalopram
Clozapine
Desvenlafaxine
Donepezil
Duloxetine
Escitalopram
Fluoxetine
Fluvoxamine
Gabapentin
Galantamine
Guanfacine
Iloperidone
Ketamine and esketamine
Lamotrigine
Lemborexant
Levetiracetam
Levomilnacipran
Lithium
Lofexidine
Lumateperone
Lurasidone
Memantine
Methylphenidate
Milnacipran
Mirtazapine
Monoamine oxidase inhibitors
Naltrexone
Nefazodone
Nonbenzodiazepine hypnotics
Olanzapine
Olanzapine-samidorphan
Opioids
Oxcarbazepine
Paliperidone
Paroxetine
Pimavanserin
Pitolisant
Quetiapine
Ramelteon
Risperidone
Rivastigmine
Serdexmethylphenidate/Dexmethylphenidate
Sertraline
Sildenafil
Suvorexant
Tasimelteon
Topiramate
Tramadol
Trazodone
Tricyclic antidepressants
Valproate/Divalproex
Vardenafil
Varenicline
Venlafaxine
Vilazodone
Vortioxetine
Ziprasidone
Appendix A. Therapeutic and Toxic Drug Levels at a Glance
Appendix B. Additional Information on Neuroimaging
Neuroimaging signal appearance: MRI and CT
Approach to reading a head CT scan
Appendix C. Additional Cardiac-Related Information
Ten rules for a normal electrocardiogram
Cardiovascular risk assessment
Medical evaluation for electroconvulsive therapy (ECT)
Appendix D. The Bilirubin Cycle
Appendix E. The Syndrome of Inappropriate Antidiuresis
References
Index
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Tags: Sandra A Jacobson, Laboratory Medicine, Psychiatry, Behavioral Science
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