Pathology for Toxicologists Principles and Practices of Laboratory Animal Pathology for Study Personnel 1st Edition by Elizabeth Mcinnes ISBN 9781118755402 1118755405

Pathology for Toxicologists Principles and Practices of Laboratory Animal Pathology for Study Personnel 1st Edition by Elizabeth Mcinnes – Ebook PDF Instant Download/Delivery: 9781118755402 ,1118755405
Full download Pathology for Toxicologists Principles and Practices of Laboratory Animal Pathology for Study Personnel 1st Edition after payment

Product details:

ISBN 10: 1118755405
ISBN 13: 9781118755402
Author: Elizabeth Mcinnes

Pathology for Toxicologists Principles and Practices of Laboratory Animal Pathology for Study Personnel 1st Edition Table of contents:

Chapter 1: An Introduction to Pathology Techniques

1.1 Animal Considerations

1.2 Necropsy

1.3 Lung Inflation with Fixative

1.4 Fixation

1.5 Making Glass Slides

1.6 Special Histochemical Stains

1.7 Decalcification

1.8 Immunohistochemistry

1.9 Tissue Crossreactivity Studies

1.10 Electron Microscopy

1.11 In Situ Hybridisation

1.12 Laser Capture Microscopy

1.13 Confocal Microscopy

1.14 Image Analysis

1.15 Digital Imaging

1.16 Spermatocyte Analysis

1.17 Good Laboratory Practice

1.18 Inhalation Studies

1.19 Continuous-Infusion Studies

1.20 Carcinogenicity

1.21 Biologicals

1.22 The Pathology Report

1.23 Conclusion

References

Chapter 2: Recording Pathology Data

2.1 What is a Pathology Finding?

2.2 Standardisation of Pathology Findings

2.3 ‘Inconsistencies’ in Pathology Recording

2.4 Blind Review

2.5 Historical Control Data: Pros and Cons

2.6 The Use of Peer Review in Pathology

References

Chapter 3: General Pathology and the Terminology of Basic Pathology

3.1 Cellular Responses to Insults

3.2 Inflammation

3.3 Circulatory Disturbances

3.4 Disorders of Tissue Growth

3.5 Tissue Repair and Healing

3.6 Neoplasia

3.7 Immune System

References

Chapter 4: Common Spontaneous and Background Lesions in Laboratory Animals

4.1 Rats

4.2 Mice

4.3 Dogs

4.4 Minipigs

4.5 Non-Human Primates

4.6 Rabbits

4.7 Experimental Procedures

4.8 Causes of Death in Rats and Mice

4.9 Conclusion

References

Chapter 5: Target Organ Pathology

5.1 Skin

5.2 Eye

5.3 Gastrointestinal Tract

5.4 Liver

5.5 Respiratory System

5.6 Urinary System

5.7 Lymphoreticular System

5.8 Musculoskeletal System

5.9 Cardiovascular System

5.10 Endocrine System

5.11 Reproductive System

5.12 Central and Peripheral Nervous System

5.13 Ear

References

Chapter 6: Clinical Pathology

6.1 Clinical Pathology in Study Phases and Good Laboratory Practice

6.2 What is Measured in Clinical Pathology?

6.3 Haematology

6.4 Coagulation

6.5 Clinical Chemistry

6.6 Urinalysis

6.7 Acute-Phase Proteins

6.8 The Biomarker Concept

6.9 Reference Intervals

6.10 Instrumentation, Validation and Quality Control

6.11 Data Analysis and Interpretation

6.12 Reporting

6.13 Food Consumption and Body Weight (Gain)

6.14 Organ Weights

6.15 Examples of Typical Clinical Pathology Profile Changes in Toxicologic Clinical Pathology

6.16 Microsampling

6.17 Conclusion

Acknowledgments

References

Chapter 7: Adversity: A Pathologist’s Perspective

7.1 LOAEL, NOEL and NOAEL: Definition

7.2 Adversity

7.3 Determining Adversity using Pathology Findings: Factors to Consider

7.4 Communicating NOAEL in Toxicity Studies

7.5 Conclusion

References

Chapter 8: Limitations of Pathology and Animal Models

8.1 Limitations of In Vivo Animal Models

8.2 Efficacy/Disease Models as Toxicology Models

8.3 Limitations of Efficacy/Disease Models as Toxicology Models

8.4 Limitations of Pathology within In Vivo Toxicology Models

8.5 Managing Risk Associated with Subjectivity and the Potential for Pathologist Error

People also search for Pathology for Toxicologists Principles and Practices of Laboratory Animal Pathology for Study Personnel 1st Edition:

pathology for toxicologists
    
b. toxicologist
    
toxicology pathology associates
    
forensic pathology toxicology
    
journal toxicologic pathology

Tags: Elizabeth Mcinnes, Toxicologists, Laboratory Animal Pathology, Study Personnel