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The Hereditary Basis of Childhood Cancer 1st Edition by David Malkin ISBN 3030744485 9783030744465

Name: The Hereditary Basis of Childhood Cancer 1st Edition by David Malkin ISBN 3030744485 9783030744465
SKU: EB-34493744
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The Hereditary Basis of Childhood Cancer 1st Edition David Malkin Digital Instant Download

Author(s): David Malkin

Edition: 1

File Details: PDF, 7.95 MB

Year: 2021

Language: english

SKU: EB-34493744 Category: Medicine Tag: David Malkin

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The Hereditary Basis of Childhood Cancer 1st Edition by David Malkin – Ebook PDF Instant Download/Delivery: 3030744485 ,9783030744465
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ISBN 10: 3030744485
ISBN 13: 9783030744465
Author: David Malkin

This volume elaborates on the research and clinical implications of the hereditary and molecular basis of childhood cancers. The focus of the ‘disease-related’ chapters of the book is to integrate what is known about the molecular basis of that particular clinical entity (or group of related entities) with the clinical manifestations, to relate the relationship of the molecular oncologic pathways with relevant developmental or non-human species biology in order to better understand the complexity of these systems. The resulting clinical implications of understanding this biology are elaborated on. Chapters 13-16 discuss the broader psychosocial, ethical and genetic counseling issues that arise and that are so critical to translating the knowledge gained from advances in molecular genetics into the clinic. Chapter 12 in particular provides a unique perspective of the application of this knowledge in less-developed nations where ‘modern’ technologies may not be readily available, butwhere the clinical manifestations of these disorders are prevalent.

The Hereditary Basis of Childhood Cancer 1st Edition Table of contents:

1. Li-Fraumeni Syndrome

2. Pediatric Central Nervous System Cancer Predisposition

3. Rhabdoid Tumors

4. Neurofibromatosis

5. Pheochromocytoma and Paraganglioma

6. Wilms Tumor

7. Hereditary Overgrowth Syndromes

8. Multiple Endocrine Neoplasias and Associated Non-endocrine Conditions

9. DICER1 Syndrome

10. Cancer-Prone Inherited Bone Marrow Failure, Myelodysplastic, and Acute Myeloid Leukemia Syndromes

11. Inherited Risk for Childhood Leukemia