The Role of Phytonutrients in Metabolic Disorders 1st Edition by Haroon Khan, Esra Akkol, Maria Daglia ISBN 9780323859790 0323859798

Section A

Chapter 1: An overview on metabolic disorders and current therapy

Abstract

1: Introduction

2: Origins of metabolic disease

3: Metabolic disorders

4: Present status and new trends on the treatment of metabolic disorders

5: Pharmacologic enzyme replacement therapy (ERT)

6: Conclusions

References

Chapter 2: Effects of phytonutrients in various metabolic pathways

Abstract

1: Introduction

2: Significance of metabolic pathways in health and diseases

3: Phytonutrients

4: Conclusions

References

Chapter 3: Nanotechnology and phytonutrients

Abstract

1: Introduction

2: Resveratrol

3: Emodin

4: Berberine

5: Curcumin

6: Quercetin

7: Other phytonutrients

8: Conclusions

References

Section B

Chapter 4: Genetic effects of phytonutrients in metabolic disorders

Abstract

1: Introduction

2: Phytonutrient-rich dietary components and genetic interactions

3: Phytonutrients/natural biomolecules targeting metabolic cell signaling pathways

4: Dietary fats involved with gene interactions in metabolic disorders

5: Conclusions

References

Chapter 5: Therapeutic role of nutraceuticals in the management of brain disorders

Abstract

Authors’ contribution

1: Introduction

2: Classes of neutraceuticals and their mechanisms of action

3: Current evidence on the use of neutraceuticals in multiple sclerosis

4: Amyotrophic lateral sclerosis and nutritional supplementations

5: Effects of neutraceuticals supplementation in Parkinson’s disease

6: Effects of nutraceuticals in Huntington’s disease

7: The role of nutraceuticals supplementation in brain ataxia

8: Proposed neuroprotective mechanisms of some popular nutraceuticals

9: Conclusions

References

Chapter 6: Phytonutrients in the management of glucose metabolism

Abstract

1: Introduction

2: Diabetes mellitus

3: Phytonutrients and DM

4: Concluding remarks

References

Chapter 7: Phytonutrients in the management of lipids metabolism

Abstract

1: Introduction

2: Disorders of lipid metabolism

3: Hypertriglyceridemia

4: Hypercholesterolemia

5: Low HDL-related abnormalities

6: Atherosclerosis

7: Obesity

8: Cancer

9: The role of phytonutrients in managing lipid-metabolism-associated disorders

10: Concluding remarks

References

Chapter 8: Cancer metabolism regulation by phytonutrients

Abstract

1: Introduction

2: Pentose phosphate pathway (PPP)

3: Serine pathway

4: Targeting enzymes of TCA by phytonutrients

5: Lactic acid fermentation

6: Other mechanisms involved in cancer metabolism and their modulation by phytonutrients

7: Clinical trials

8: Bioavailability of phytonutrients

9: Synergistic effects of phytonutrients

10: Conclusions

References

Chapter 9: Acid-base and electrolyte balance regulations with phytonutrients

Abstract

1: Introduction

2: Acid-base balance regulations

3: Phytonutrients

4: Regulation of acid-base and electrolyte balance with phytonutrients

5: Conclusions

References

Chapter 10: Therapeutic role of nutraceuticals in mitochondrial disorders

Abstract

1: Introduction

2: Mitochondrial disorders

3: Therapeutic nutraceuticals

4: Traditional nutraceuticals

5: Plant-based nutraceuticals

6: Fruit- and vegetable-based nutraceuticals

7: Nutraceutical biocatalyst

8: Nontraditional nutraceuticals

9: Molecular mechanisms/targeting signaling pathway

10: Nutraceuticals interact with protein misfolding and endoplasmic reticulum stress pathway

11: Combined effects of nutraceuticals

12: Interaction of nutraceuticals with medicines

13: Regulatory challenges of nutraceuticals

14: Conclusions

References

Chapter 11: Phytonutrients in regulation of malabsorption disorders

Abstract

1: Summary

2: Introduction

3: Pathophysiology of malabsorption

4: The role of phytonutrients in management of malabsorption-related disorders

5: Conclusions

References

Chapter 12: Skin metabolic syndrome and phytonutrients

Abstract

Acknowledgment

1: Introduction

2: Metabolic syndrome and skin diseases

3: Phytochemicals in metabolic syndrome

4: Conclusions

References

Chapter 13: Cachexia and phytonutrients

Abstract

1: Introduction

2: Cachexia and molecular mechanisms: Targeted signaling pathways

3: Effect of natural products on cachexia

4: Conclusions

References

Index