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Viral and Fungal Infections of the Central Nervous System A Microbiological Perspective 1st Edition by Hiba Sami, Safiya Firoze, Parvez A Khan ISBN 981996444X 978-9819964444

Name: Viral and Fungal Infections of the Central Nervous System A Microbiological Perspective 1st Edition by Hiba Sami, Safiya Firoze, Parvez A Khan ISBN 981996444X 978-9819964444
SKU: EB-54299912
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Viral and Fungal Infections of the Central Nervous System A Microbiological Perspective 1st Edition Hiba Sami Safiya Firoze Parvez A Khan Digital Instant Download

Author(s): Hiba Sami Safiya Firoze Parvez A Khan

Edition: 1

File Details: PDF, 8.59 MB

Year: 2023

Language: english

SKU: EB-54299912 Category: Medicine - Infectious diseases Tag: Hiba Sami Safiya Firoze Parvez A Khan

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ISBN 10: 981996444X

ISBN 13: 978-9819964444

Author: Hiba Sami, Safiya Firoze, Parvez A Khan

This book covers topics related to viral and fungal infections of the central nervous system (CNS), with a multidisciplinary reach, discussing associated immunology, microbiological aspects, pathologies, timely management, and prevention. The book is structured into five broad sections.

The first section provides the reader with valuable insights into the aetiologies and underlying pathophysiological mechanisms of neurological diseases, including host responses. It mentions all bacterial, fungal, parasitic, and viral causes of neuro-infections, along with rarer neuropathogenesis such as prions and mycoplasmas. The chapter also presents detailed epidemiology and prevalence of different CNS infections worldwide. It also reviews various infectious diseases that target the nervous system, such as focal lesions, meningitis, and neurological complications of venous sinus thrombosis. The next two sections delve deep into pathogen-specific diseases of the CNS, namely the virusesand fungi associated with neuro-infections. It mentions detailed excerpts on encephalitic viruses, long-term consequences of neurotropic viruses, mycological neuroinfectious, and even the emerging, less talked of viruses and fungi causing neurological disease. Topics such as principles of vigorous antifungal therapy and surgeries are also discussed in the chapter. The fourth section gives an insight on prospects for efficiently diagnosing and managing viral and fungal CNS infections, to tackle associated morbidities.

Features that are often less documented, yet of considerable interest in current times, such as the role of immunosuppression in neurological infections and newer microbiological diagnostic strategies are covered. The last section uniquely provides clinicians with relatable case scenarios. Real case descriptions are included, such as cases of fungal meningitis and other difficult-to-diagnose infections produced by viruses. This book serves as a guide for neurologists, medical microbiologists, and clinical practitioners who deal with patients suspected of neurological infection.

Viral and Fungal Infections of the Central Nervous System A Microbiological Perspective 1st Table of contents:

Preface

Introduction to the topic
Scope and objectives of the book
Target audience

Chapter 1: Introduction to CNS Infections

Overview of the Central Nervous System (CNS)
Mechanisms of Infection in the CNS
Key Risk Factors for CNS Infections
Pathogenesis of Viral and Fungal Infections in the CNS

Chapter 2: General Microbiological Principles in CNS Infections

Microbial Entry into the CNS
Host Immune Response and Neuroinflammation
Diagnostic Approaches: Techniques and Challenges
Blood-Brain Barrier and Pathogen Access

Chapter 3: Viral Infections of the CNS

Overview of Viral Pathogens in the CNS
Mechanisms of Viral Neurotropism
Common Viral Infections of the CNS (Herpes Simplex, Varicella-Zoster, HIV, etc.)
Emerging Viral Threats to the CNS (Zika, Ebola, etc.)

Chapter 4: Herpes Simplex Virus (HSV) and the CNS

HSV-1 and HSV-2 Infections in the CNS
Pathophysiology of HSV Encephalitis
Diagnosis and Treatment of HSV CNS Infections
Long-term Neurological Outcomes

Chapter 5: Arboviruses and CNS Pathogenesis

Mosquito-borne Viruses (West Nile, Dengue, Zika)
Mechanisms of Arboviral Neuroinvasion
Diagnosis and Clinical Management
Case Studies: Clinical Presentations and Outcomes

Chapter 6: Fungal Infections of the CNS

Overview of Fungal Pathogens in the CNS
Mechanisms of Fungal CNS Invasion
Risk Factors and Host Immunity in Fungal Infections
Common Fungal Infections of the CNS (Cryptococcus, Candida, Aspergillus, etc.)

Chapter 7: Cryptococcal Meningitis and Other Fungal Infections

Pathogenesis of Cryptococcal Meningitis
Clinical Presentation and Diagnosis
Treatment Strategies for Fungal CNS Infections
Management of Immunocompromised Patients

Chapter 8: Diagnostic Tools for CNS Viral and Fungal Infections

Clinical Evaluation and Neuroimaging
Laboratory Diagnostics: PCR, Serology, Culture Techniques
New and Emerging Diagnostic Technologies (Metagenomics, Next-Generation Sequencing)
Case Examples of Diagnostic Challenges

Chapter 9: Treatment Strategies for Viral and Fungal CNS Infections