Vitamin D Basic Research and its Clinical Application 1st Edition by AW Norman ISBN 9783112330029 3112330021

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ISBN 10: 3112330021
ISBN 13: 9783112330029
Author: AW Norman

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Vitamin D Basic Research and its Clinical Application 1st Edition Table of contents:

Part I: Synthesis and Structural Studies

• Synthesis of Some Side Chain Analogues of Vitamin D₃ Metabolites

• Structural Transformations on Vitamin D

• Distribution and Activity of a Vitamin D₃ Compound in Trisetum Flavescens

• Synthesis and Biological Activity of Fluorinated Cholecalciferols

• Fluorinated Analogues as Probes of Vitamin D Metabolism

• Substituted Dihydrovitamins via Hydrozirconation

• Synthesis of Dihydroxy Methylcholesta Compounds

• Isomerization of Vitamin D Isomers

• Use of Spectroscopic Methods in Vitamin D Research

Part II: Metabolism and Biochemistry

• The Role of the Liver in Vitamin D Metabolism

• Prostaglandins and Hydroxylase Activity

• Regulation of Plasma Vitamin D in Dogs

• Essential Role of Vitamin D Metabolites in Mineral Homeostasis

• Renal Metabolites in Chickens

• Enzyme Pathways in Vitamin D Hydroxylation

• Hydroxylase Regulation in Cultured Kidney Cells

• Extra-Renal Hydroxylase Activity in Pregnancy

Part III: Biological Activity and Pharmacology

• Biological Activity in Rats

• Inhibitors of Vitamin D Metabolism

• C1-Hydroxylation of Vitamin D₃

• Vitamin D₃ Sulfate in Lactating Rats and Pups

• Covalent Binding of Vitamin D Analogues to Chromatographic Media

Part IV: Clinical Applications

• Osteoporosis

• Role of Vitamin D in Intestinal Calcium Absorption

• Clinical Studies in Osteoporosis Treatment

• Binding Proteins and Transport

• Structure of Human Plasma Vitamin D Transport Proteins

• Gc Polymorphism and Binding

• Sunlight and Seasonal Effects on Vitamin D

• Skin Synthesis in Nutrition Support Patients

• Photobiochemistry in the Skin

Part V: Analytical Techniques

• Assays for Vitamin D Metabolites

• Use of Isotope Dilution and Mass Spectrometry

• Radioimmunoassays and Liquid Chromatography

• Technical Considerations in Assays

• Radiocompetitive Protein Binding

Part VI: Hormonal Interactions

• Vitamin D and Parathyroid Hormone

• Hormonal Regulation in Pregnancy and Animal Studies

• Thyroid and Parathyroid Interactions

• Receptor Studies in Bone and Kidney

• Endocrine Responses to Vitamin D Derivatives

Part VII: Maternal, Fetal, and Pediatric Considerations

• Vitamin D in Preterm Infants

• Transplacental Metabolism

• Veterinary Studies on Pregnancy and Vitamin D

• Nutritional Deficiencies and Fetal Development

Part VIII: Skeletal Effects

• Vitamin D in Epiphyseal Calcification

• Histological Effects on Bone

• Bone Mineralization and Preferred Metabolites

• Dual Actions on Bone Metabolism

• In Vitro and In Vivo Studies in Bone Cells

Part IX: Kidney and Metabolic Function

• Vitamin D Activation in Kidney Tubules

• Hormonal Influence on Renal Metabolism

• Chronic Ethanol Effects on Vitamin D Metabolism

• Calcium Restriction and Vitamin D Response

• Modeling and Simulation of Vitamin D Pathways

Part X: Gastrointestinal and Nutritional Interactions

• Calcium-Binding Protein in the Intestine

• Microscopy of Calcium Transport

• High-Dose Vitamin D Effects in Poultry

• Purification of Intestinal Receptors

• Nutritional Studies in Vitamin D Deficiency

• Radioimmunoassay Applications in GI Research

Part XI: Renal Osteodystrophy and Therapy

• Diagnosis and Treatment Studies

• Hyperparathyroidism and Vitamin D Resistance

• Long-Term Vitamin D Therapy Results

• Clinical Trials Across Multiple Centers

• Effects of Dihydrotachysterol and Other Analogs

• Histomorphometric Analyses

Part XII: Related Diseases and Disorders

• Hypophosphatemia and Renal Disorders

• Diabetes and Vitamin D Interaction

• Sarcoidosis and Vitamin D Abnormalities

• Malabsorption Syndromes

• Glomerular Disease in Children

• Magnesium Metabolism and Vitamin D

Part XIII: Final Considerations

• Vitamin D Assay Use in Veterinary Settings

• Growth Hormone Interactions

• Gastric and Duodenal Absorption Studies

• Hypoparathyroid Patient Case Study

• Phosphoglyceride Composition Alteration

• Nomenclature and Unresolved Clinical Questions

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Tags: AW Norman, Vitamin D, Basic Research, Clinical Application