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Digital Twins Applications to the Design and Optimization of Bioprocesses 1st Edition by Christoph Herwig, Ralf Pörtner, Johannes Möller ISBN 9783030716561 3030716562

Name: Digital Twins Applications to the Design and Optimization of Bioprocesses 1st Edition by Christoph Herwig, Ralf Pörtner, Johannes Möller ISBN 9783030716561 3030716562
SKU: EB-43068690
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Digital Twins Applications to the Design and Optimization of Bioprocesses 1st Edition Christoph Herwig Digital Instant Download

Author(s): Christoph Herwig, Ralf Pörtner, Johannes Möller

ISBN(s): 9783030716554, 9783030716592, 9783030716561, 3030716554, 3030716562, 3030716597

Edition: 1

File Details: PDF, 8.91 MB

Year: 2021

Language: English

SKU: EB-43068690 Category: Engineering - Bioengineering Tags: Christoph Herwig, Johannes Möller, Ralf Pörtner

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Digital Twins Applications to the Design and Optimization of Bioprocesses 1st Edition by Christoph Herwig, Ralf Pörtner, Johannes Möller – Ebook PDF Instant Download/Delivery: 9783030716561 ,3030716562
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Product details:
ISBN 10: 3030716562
ISBN 13: 9783030716561
Author: Christoph Herwig, Ralf Pörtner, Johannes Möller

This is the second of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization. Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into the 21st-century digitalization of the bioprocess industry. Moreover, the high demand for biotechnological products calls for efficient methods during research and development, as well as during tech transfer and routine manufacturing. In this regard, one promising tool is the use of digital twins, which offer a virtual representation of the bioprocess. They reflect the mechanistics of the biological system and the interactions between process parameters, key performance indicators and product quality attributes in the form of a mathematical process model. Furthermore, digital twins allow us to use computer-aided methods to gain an improved process understanding, to test and plan novel bioprocesses, and to efficiently monitor them. This book focuses on the application of digital twins in various contexts, e.g. computer-aided experimental design, seed train prediction, and lifeline analysis. Covering fundamentals as well as applications, the two volumes offers the ideal introduction to the topic for researchers in academy and industry alike.

Digital Twins Applications to the Design and Optimization of Bioprocesses 1st Edition Table of contents:

Potential of Integrating Model-Based Design of Experiments Approaches and Process Analytical Technologies for Bioprocess Scale-Down
Digital Twins and Their Role in Model-Assisted Design of Experiments
Digital Twins for Bioprocess Control Strategy Development and Realisation
The Kalman Filter for the Supervision of Cultivation Processes
The Challenge of Implementing Digital Twins in Operating Value Chains
Digital Twins: A General Overview of the Biopharma Industry
Numerical Methods for the Design and Description of In Vitro Expansion Processes of Human Mesenchymal Stem Cells
Euler-Lagrangian Simulations: A Proper Tool for Predicting Cellular Performance in Industrial Scale

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Tags: Christoph Herwig, Ralf Pörtner, Johannes Möller, Digital Twins Applications, Optimization, Bioprocesses