Foot and Mouth Disease Virus Current Research and Emerging Trends 1st Edition by Francisco Sobrino, Esteban Domingo 1910190519 978-1910190517

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ISBN 10: 1910190519
ISBN 13: 978-1910190517
Author: Francisco Sobrino, Esteban Domingo

This book is required reading for everyone involved in FMD and is an important acquisition for all microbiology libraries. The volume provides essential scientific background on FMD and its etiological agent, FMD virus, as well as comprehensive, interdisciplinary and up-to-date information on basic research findings and applied developments contributing to FMD control. The eighteen chapters have been written by leading FMD researchers. Topics include genome organization, translation and replication, virus-coded proteinases, structure of virus particles, cell receptors and host range, the RNA polymerase, quasispecies dynamics and virus evolution, innate and acquired immune responses, and the clinical signs of FMD and its natural habitats. Further chapters deal with various aspects of disease control such as diagnosis, current and new vaccines, antivirals and models of epidemiology. The role of international organizations in FMD control and the impact of FMDV as a re-emergent virus are also addressed

Foot and Mouth Disease Virus Current Research and Emerging Trends 1st Table of contents:

Introduction: Foot-and-mouth Disease – Much Progress But Still a Lot to Learn
David J. Rowlands

Chapter 1: Genome Organization, Translation and Replication of Foot-and-mouth Disease Virus RNA
Encarnación Martinez-Salas and Graham J. Belsham

Chapter 2: Foot-and-mouth Disease Virus Proteinases and Polyprotein Processing
Fiona Tulloch, Garry A. Luke and Martin D. Ryan

Chapter 3: The Foot-and-mouth Disease Virion: Structure and Function
Mauricio G. Mateu

Chapter 4: Foot-and-mouth Disease Virus Receptors: Multiple Gateways to Initiate Infection
Paul Lawrence and Elizabeth Rieder

Chapter 5: The RNA-dependent RNA Polymerase 3D: Structure and Fidelity
Cristina Ferrer-Orta and Nuria Verdaguer

Chapter 6: Quasispecies Dynamics Taught by Natural and Experimental Evolution of Foot-and-mouth Disease Virus
Esteban Domingo, Ignacio de la Higuera, Elena Moreno, Ana I. de Ávila, Rubén Agudo, Armando Arias and Celia Perales

Chapter 7: Clinical Signs and Pathology of Foot-and-mouth Disease
Charles Nfon, Oliver Lung, Carissa Embury-Hyatt and Soren Alexandersen

Chapter 8: Natural Habitats in which Foot-and-mouth Disease Viruses are Maintained
Wilna Vosloo and Gavin R. Thomson

Chapter 9: Innate to Adaptive: Immune Defence Handling of Foot-and-mouth Disease Virus
Kenneth C. McCullough, Margarita Sáiz and Artur Summerfield

Chapter 10: Laboratory Diagnostic Methods to Support the Surveillance and Control of Foot-and-mouth Disease
Anna Ludi, Valerie Mioulet, Nick J. Knowles and Donald P. King

Chapter 11: Quality Attributes of Current Inactivated Foot-and-mouth Disease Vaccines and Their Effects on the Success of Vaccination Programmes
Eliana N. Smitsaart and Ingrid E. Bergmann

Chapter 12: Peptide Vaccines Against Foot-and-mouth Disease
Esther Blanco, David Andreu and Francisco Sobrino

Chapter 13: Control of Foot-and-mouth Disease by Using Replication-defective Human Adenoviruses to Deliver Vaccines and Biotherapeutics
Fayna Diaz-San Segundo, Gisselle N. Medina, Marvin J. Grubman and Teresa de los Santos

Chapter 14: Antiviral Therapies for Foot-and-mouth Disease
Annebel R. De Vleeschauwer, David J. Lefebvre and Kris De Clercq

Chapter 15: Mathematical Models of the Epidemiology and Control of Foot-and-mouth Disease
Michael J. Tildesley, William J.M. Probert and Mark E.J. Woolhouse

Chapter 16: The Role of International Organizations in the Control of Foot-and-mouth Disease
Bernard Vallat, Joseph Domenech and Alejandro A. Schudel

Chapter 17: Overview of Foot-and-mouth Disease and its Impact as a Re-emergent Viral Infection
Brian W.J. Mahy and Graham J. Belsham

Index

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Francisco Sobrino,Esteban Domingo,Mouth Disease