Optical Polarimetric Modalities for Biomedical Research Biological and Medical Physics Biomedical Engineering 1st editon by Nirmal Mazumder, Yury Kistenev, Ekaterina Borisova, Shama Prasada 3031318528 9783031318528

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ISBN 10: 3031318528
ISBN 13: 9783031318528
Author:  Nirmal Mazumder, Yury V. Kistenev, Ekaterina Borisova, Shama Prasada K.

This book focuses on polarization microscopy, a powerful optical tool used to study anisotropic properties in biomolecules, and its enormous potential to improve diagnostic tools for various biomedical research. The interaction of polarized light with normal and abnormal regions of tissue reveals structural information associated with its pathological condition. Diagnosis using conventional microscopy can be time-consuming, as pathologists require an hour to freeze and stain tissue slices from suspected patients. In comparison, polarization microscopy more quickly distinguishes abnormal tissue and provides better microstructural information of samples, even in the absence of staining. This book provides a basic understanding of the properties of polarized light, a description of the polarization microscope, and a mathematical formalism of Mueller matrix polarimetry. The authors discuss various advanced linear and nonlinear optical techniques such as optical coherence tomography (OCT), reflectance and transmission spectroscopy, fluorescence, multiphoton excitation, second harmonic generation, Raman microscopy, and more. They explore the exciting potential of integrating polarimetry with these techniques for possible applications in different areas of biomedical research, as well as the associated challenges. Including the most recent developments on the topic, this book serves as a modern guide to polarization microscopy and advancements in its use in biomedical research.

Optical Polarimetric Modalities for Biomedical Research Biological and Medical Physics Biomedical Engineering 1st Table of contents:

Part I. Stokes Mueller Based Polarimetry

1. Polarization Imaging of Optical Anisotropy in Soft Tissues

2. Polarization Techniques in Biological Microscopy

3. Stokes–Mueller Matrix Polarimetry: Effective Parameters of Anisotropic Turbid Media: Theory and Application

4. Mueller Matrix Imaging

5. Biological Imaging Through Optical Mueller Matrix Scanning Microscopy

6. Mueller Polarimetry for Biomedical Applications

7. Scattering Phase Functions and Polarimetric Responses of Selected Bioparticles

Part II. Nonlinear Polarization Microscopy

8. Polarization-Resolved Nonlinear Optical Microscopy

9. Polarization-Resolved SHG Microscopy for Biomedical Applications

10. Polarization-Resolved Second-Harmonic Generation for Tissue Imaging

Part III. Applications of Polarization Techniques

11. An Introduction to Fundamentals of Cancer Biology

12. Polarization-Enabled Optical Spectroscopy and Microscopic Techniques for Cancer Diagnosis

13. Polarization Microscopy in Biomedical Applications

14. Machine Learning in Tissue Polarimetry

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Nirmal Mazumder,Yury Kistenev,Ekaterina Borisova,Shama Prasada,Optical Polarimetric Modalities