Testosterone From Basic to Clinical Aspects 1st edition by Alexandre Hohl ISBN ‎ 3319460846 978-3319460840

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ISBN 10: ‎ 3319460846
ISBN 13:  978-3319460840
Author: Alexandre Hohl

Research on testosterone is increasing in many senses; however there is still much controversy regarding its physiology and clinical use. This book addresses these topics, providing a broad over­view about testosterone, from its basic fea­tures to the most recent evidence of clin­ical applicability. Also, specific conditions in which testosterone play a pivotal role are discussed in detail, such as hypogonadism, misuse and abuse, puberty, cardiovascular effects and testosterone therapy. Although not essential for survival, testosterone represents the essence of male biological function, being the important testicular androgen in men. Low serum testosterone levels are asso­ciated with cardiovascular morbidity, meta­bolic syndrome, type 2 diabetes mellitus, atherosclerosis, osteoporosis, sarcopenia, and mortality. Conversely, increased serum levels of testosterone may lead to deleteri­ous events. In general, there is increasing evidence that serum testosterone is a major biomarker status of men’s health in general.

Testosterone: From Basic to Clinical Aspects is an indispensable reference for all those who seek state-of-the-art knowledge regarding this hormone, from basic issues (including pharma­cology and physiology) through clinical aspects (related diseases and supplementation ther­apy).

Testosterone From Basic to Clinical Aspects 1st Table of contents:

Preface

• Introduction to Testosterone and Its Importance

Chapter 1: Overview of Testosterone

• The Role of Testosterone in the Body
• History and Discovery of Testosterone
• Synthesis and Regulation of Testosterone
• Testosterone in Both Men and Women

Chapter 2: Basic Biology of Testosterone

• Mechanism of Action: Androgen Receptors
• Testosterone Metabolism
• Transport and Bioavailability of Testosterone
• Physiological Effects of Testosterone on Organs and Tissues

Chapter 3: Regulation of Testosterone

• Hypothalamic-Pituitary-Gonadal (HPG) Axis
• Factors Affecting Testosterone Levels
• Feedback Mechanisms in Testosterone Regulation
• Age-Related Changes in Testosterone

Chapter 4: Testosterone and Reproductive Health

• Testosterone’s Role in Male Development and Puberty
• Female Reproductive Health and Testosterone
• Effects of Testosterone on Fertility and Reproductive Function
• Disorders Related to Testosterone Imbalance (e.g., Hypogonadism, PCOS)

Chapter 5: Testosterone and Metabolism

• Testosterone’s Influence on Muscle Mass and Bone Health
• Impact of Testosterone on Fat Distribution and Obesity
• Cardiovascular Health and Testosterone
• Testosterone and Insulin Sensitivity

Chapter 6: Testosterone in Aging and Health

• The Aging Male: Testosterone Decline and Symptoms
• Andropause: Symptoms and Treatment Options
• Testosterone Replacement Therapy (TRT) in Older Adults
• Potential Benefits and Risks of Testosterone Therapy

Chapter 7: Testosterone and Psychological Function

• Testosterone and Mood Disorders
• Cognitive Function and Testosterone
• The Link Between Testosterone and Aggression
• Testosterone in Mental Health Disorders

Chapter 8: Testosterone and Clinical Applications

• Diagnosis of Testosterone Deficiency
• Testosterone Replacement Therapy (TRT): Indications and Methods
• Approaches to Managing Hypogonadism
• Ethical and Safety Considerations in Testosterone Therapy

Chapter 9: Pathological Conditions and Testosterone Imbalance

• Hypogonadism: Causes and Treatments
• Testosterone and Prostate Health
• Disorders of Testosterone Excess (e.g., Hyperandrogenism, Tumors)
• Testosterone and Metabolic Syndromes

Chapter 10: Future Directions in Testosterone Research and Therapy

• Advances in Testosterone Measurement and Monitoring
• Novel Therapeutic Approaches
• Emerging Controversies and Ethical Challenges in Testosterone Use
• The Future of Precision Medicine and Testosterone Management

Appendix

• Glossary of Terms
• Index
• References

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Alexandre Hohl,Clinical Aspects,Testosterone