Theoretical Genetics 1s Edition by Richard B Goldschmidt ISBN 9780520346352 0520346351

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ISBN 10: 0520346351
ISBN 13: 9780520346352
Author: Richard B Goldschmidt

Theoretical Genetics 1s Edition Table of contents:

1 THE CHROMOSOME AND ITS DIVISION

2 GENIC AND NON-GENIC PARTS OF THE CHROMOSOME

A. CONCLUSIONS FROM MORPHOLOGY

B. CONCLUSIONS FROM BIOCHEMISTRY a. Chemistry of the chromosome

aa. Quantitative constancy of DNA

bb. Information derived from the structure of the nucleic acid molecule

cc. Conclusions from bacterial transformation and transduction

dd. Some additional relevant facts

c. General conclusions

C. HETEROCHROMATIN

a. The cytological aspect

b. Chromatin diminution and related phenomena

c. Interpretations derived from the cytological facts

d. Cytology and genetics of heterochromatin in Drosophila

aa. Chromocentric and Y-chromosomal heterochromatin

bb. Genetic functions? Chromosomal breaks and heterochromatin

cc. Intercalary heterochromatin

dd. Genetic function of intercalary heterochromatin

ee. Heterochromatin and the genetics of sex

3 CHROMOSOMES AND GENES

A. THE THEORY OF THE GENE

B. THE THEORY OF THE GENE MOLECULE a. Treffer theory

b. Return mutation

c. Counting the genes

C. THE THEORY OF CHROMOSOMAL HIERARCHY

a. Precursor ideas

b. Chromosome breakage

c. Position effect

aa. The Bar case

bb. Frequency and types

cc. Some special features

dd. Position effect and point mutation

ee. Theory of position effect and genic structure of the chromosome

ff. On allelism

d. Further members of the hierarchy aa. Larger segments

bb. The chromosome as a whole

D. CONCLUSIONS: THE MODERN THEORY OF THE GENE

1 PROLEGOMENA

2 THE CYTOPLASM AS SPECIFIC SUBSTRATE

A. MATERNAL INHERITANCE AND CONDITIONING OF THE CYTOPLASM

B. DAUERMODIFIKATION

C. PLASMON ACTION OF THE SPECIFIC SUBSTRATE TYPE

a. Mendelian segregation in different cytoplasm

b. Genomes in different cytoplasm

c. Evidence from merogony

D. GENUINE PLASMON

E. CYTOPLASMIC HEREDITY OF THE PARTICULATE TYPE (PLASMAGENES)

a. Genoids

b. So-called cytoplasmic mutation in yeast

c. The killer effect

d. The plastids aa. Nature of plastids

bb. Plastids and surrounding cytoplasm

cc. Primary plastid differences

3 CONCLUSIONS AND THEORETICAL

INTRODUCTION

A Generalized Example 253

3 PHENOCOPY AND NORM OF REACTION

A. NORM OF REACTION

B. PHENOCOPY AND MUTATION

C. CHEMICAL PHENOCOPIES

4 PRIMARY ACTIONS

A. THE CHROMOSOMAL SITE

B. THE INTRANUCLEAR SITE

C. SPECIAL THEORIES OF GENIC ACTION

a. The one gene—one action theory

b. Relation to other ideas

5 GENIC CONTROL OF DEVELOPMENT

A. THE QUALITATIVE ASPECT a. Nuclear versus cytoplasmic diversification

b. Biochemical attack

B. THE CYTOPLASMIC SUBSTRATE OF GENIC ACTION

a. Basic deliberations

b. Specific ideas derived from embryology

c. Activation of the genes

C. KINETICS OF GENIC ACTION

a. Dosage of genic material

aa. Dosage in sex determination

bb. Dosage within allelism

cc. Dosage in sex linkage

dd. Multiple factors and dosage

b. Dominance, potency, penetrance

c. Dosage via chromosomes

D. GENIC ACTION IN FOUR DIMENSIONS

a. Factorial collaboration

b. Pleiotropy

c. The time dimension

d. Short cuts: inductors, hormones

e. Mutational changes of determination; regulation and integration

E. SYNOPSIS

INTRODUCTION

3 DIFFERENT GENETIC POSSIBILITIES WITHIN THE BALANCE THEORY

A. VARIANTS IN REGARD TO SEX DETERMINERS

B. VARIANTS WITHIN THE BALANCE SYSTEM

a. Female heterogamety

b. Male heterogamety

c. The Melandrium case

d. Dioecism derived from monoecism in other cases

e. Once more the Y-chromosome

4 BALANCE AND MODIFICATION

5 MONOECISM AND INTERSEXUALITY a. Introduction

b. Shift of sex expression in maize

c. Monoecism and intersexuality in Streptocarpus

d. The embryological side of the problem

6 DIFFERENT TYPES OF SEX DETERMINATION

A. SO-CALLED PHENOTYPIC SEX DETERMINATION

B. MULTIFACTORIAL SEX DETERMINATION?

C. SEX IN HAPLOIDS

D. THE HYMENOPTERA TYPE

1 INTRODUCTION

2 EVOLUTION OF THE GENIC MATERIAL

3 EVOLUTION AND GENIC ACTION

BIBLIOGRAPHY

INDEX OF AUTHORS

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Tags: Richard B Goldschmidt, Theoretical Genetics